Bioactive and antibacterial hybrid coatings for complex geometry surgical orthopedic and dental implants

 

Investigator: Professor Dr.-Ing. Josefina Ballarre (Visiting researcher, INTEMA, National University of Mar del Plata, Argentina)

 

Josefina Ballarre

Collaborator: Prof. Dr.-Ing. habil. Aldo R. Boccaccini

 

This project is being carried on as a part of an Experienced Researchers Georg Forster Research Fellowship of the Alexander von Humboldt Fellowship (2018) awarded to Prof. Dr-Ing. Josefina Ballarre, from INTEMA, National University of Mar del Plata, Argentina. The main challenge of this project is to apply two different and cost-effective technologies (spray deposited hybrid organic-inorganic (with bioactive particles) sol gel coating [1,2] and electrophoretic deposition (EPD) of gelatin-chitosan-silica antibiotic coating [3, 4]) to modify the surface of typical implantological screw-shaped metals such as stainless steel (temporary) and titanium (permanent). The bilayered deposit will create a dual multifunctional coating able to protect against corrosion, induce bone formation and reduce infection risks.

[1] Gonzalez Galdos M. V., Pastore J., Ballarre J, Ceré S. M., Dual surface modification on titanium alloy with anodizing treatment and bioceramic particles for enhancing prosthetic devices, J. Mater Sci. 52 (2017) 9151–9165.

[2] Omar, S.A., Ballarre, J., Ceré S.M., Protection and functionalization of AISI 316 L for orthopedic implants: hybrid coating and sol gel glasses by spray to promote bioactivity, Electrochimica Acta 203 (2016) 309–315.

[3]Pishbin F., Mouriño V., Flor S., Kreppel S., Salih V., Ryan M.P., Boccaccini A.R., Electrophoretic deposition of gentamicin-loaded bioactive glass/chitosan composite coatings for orthopaedic implants, ACS Appl Mater Interfaces. 6 (2014) 8796-806.

[4] Heise, S., et al., Electrophoretic deposition of chitosan/bioactive glass/silica coatings on stainless steel and WE43 Mg alloy substrates, Surface and Coatings Technology 344 (2018) 553-563.